Knowing yourself pregnant tentusaja make you become more cautious in consuming drugs. Hopefully this article useful to you.Indonesia is still using the criteria of drug safety for pregnant women that was launched by the FDA (Food and Drug Administration) as a guide in giving the drug in pregnant women. In this post I show only the outlines of the limitations of drug safety for pregnant women who are arranged in five categories (categories A, B, C, D and X) along with examples that are known mother in the hope of providing useful information. These categories are based on the presence or absence of (large size) the risk of reproductive system, adverse effects and expected benefits.




Drug Category A: is a class of drugs in the study (controlled) in pregnancy showed no risk to the fetus in the first trimester and the next trimester. Drugs in this category is very unlikely for fetal safety.Drug Category B: is a class of drugs in the study of the reproductive system of experimental animals showed no risk to the fetus. There are no controlled studies in pregnant women who showed any side effects, except for a decrease in fertility in the first trimester of pregnancy, whereas in the next trimester found no evidence of risk. Drug Category C: is the class of drugs in the study of the reproductive system of experimental animals showed any side effects to the fetus. While in pregnant women has been no controlled study. These drugs can be used only if the benefits outweigh the possible risks to the fetus. Drug Kategoti D: is the class of drugs that show the risk to the fetus. In special circumstances these drugs are used if the benefits probably outweigh the risks. Use of this class of drugs, especially to cope with life-threatening situation or if there is no other drug is safer. Drug Category X: is the class of drugs in the study of experimental animals and in humans show evidence of risk to the fetus. These drugs should not be used (contraindicated) for pregnant women, or possibly in a state of pregnancy. EXAMPLE OF A DRUG CATEGORY (Generic name): - Ascorbic acid (vitamin C) * category C if dose exceeds the U.S. RDA *, - Doxylamine, ergocalciferol * category D if dosage exceeds the U.S. RDA *, - Folic acid * category C if dose exceeds 0.8 mg per day *, - Hydroxocobalamine * category C if dose exceeds the U.S. RDA *, - Liothyronine, nystatin vaginal soup * category C when used orally and topically *, - Pantothenic acid * category C if dose exceeds the U.S. RDA *, - Potassium chloride, Potassium citrate, Potassium gluconate, Pyridoxine (vitamin B6), Riboflavin * category C if dose exceeds the U.S. RDA *, - Thiamine (vitamin B1) * category C if dose exceeds the U.S. RDA *, - Thyroglobulin, thyroid hormones, Vitamin D * in the category D if dosage exceeds the U.S. RDA *, - Vitamin E * category C if dose exceeds the U.S. RDA *. EXAMPLES OF CATEGORY B DRUG (Generic name): - Acetylcysteine, Acyclovir, amiloride * category D if used for hypertension induced by pregnancy * - Ammonium chloride, Ammonium lactate topical * *, - Amoxicillin, Amphotericin B, Ampicillin, Atazanavir, Azatadine, Azelaic acid, Benzylpenicillin, Bisacodyl, * inhaled budesonide, nasal *, - Buspiron, Caffeine, Carbenicillin, Camitine, Cefaclor, Cefadroxil, Cefalexin, Cefalotin, Cefamandole, Cefapirin, Cefatrizine, Cefazolin, Cefdinir, Cefditoren, Cefepime, Cefixime, Cefmetazole, Cefonicid, Cefoperazone, Ceforanide, cefotaxime, disodium Cefotetan, Cefoxitin, Cefpodoxime, Cefprozil, Cefradine, ceftazidime, Ceftibuten, Ceftizoxime, Ceftriaxone, cefuroxime, cetirizine, Chlorhexidine mouth and throat * *, - Chlorpenamine, Chlortalidone * category D if used for hypertension induced by pregnancy *, - Ciclacillin, Ciclipirox, Cimetidine, Clemastine, clindamycin, Clotrimazole, cloxacillin, Clozapine, Colestyramine, and much more. EXAMPLES OF CATEGORY C DRUG (Generic name): Acetazolamide, Acetylcholine chloride, adenosine, albendazole, albumin, Alclometasone, Allopurinol, Aluminium hydrochloride, aminophylline, Amitriptyline, Amlodipine, Antazoline, Astemizole, Atropine, Bacitracin,   Beclometasone, Belladonna, Benzatropine mesilate, benzocaine, Buclizine, Butoconazole, Calcitonin, Calcium acetate, Calcium ascorbate, Calcium carbonate, Calcium chloride, Calcium citrate, Calcium folinate, Calcium glucoheptonade, Calcium gluconate, calcium lactate, calcium phosphate, calcium polystyrene sulfonate, Capreomycin, Captopril, Carbachol, carbidopa, Carbinoxamine, chloral hydrate, Chloramphenicol, Chloroquine, Chlorothiazide, chlorpromazine, Choline theophyllinate, Cidofovir, Cilastatin, Cinnarizine, Cyprofloxacin, cisapride, Clarithromycin, Clinidium bromide, Clonidine, Co-trimoxazole, Codeine, Cyanocobalamin, Deserpidine, Desonide, Desoximetasone, Dexamethasone, dextromethorphan, digitoxin, Digoxin, Diltiazem, Dopamine, Ephedrine, epinephrine, Fluconazole, Fluocinolone, Fosinopril, Furosemide, Gemfibrozil, gentamicin, glibenclamide, glimepiride, glipizide, Griseofulvin, hydralazine, Hydrocortisone, Hyoscine, Hyoscyamine, Isoniazid, Isoprenaline, Isosorbid dinitrate, Ketoconazole, ketotifen fumarate, Magaldrate, Mefenamic acid, methyl prednisolone, and much more. EXAMPLE OF DRUG CATEGORY D (Generic name): Amikacin, amobarbital, atenolol, Carbamazepine, Carbimazole, Chlordizepoxide, Cilazapril, Clonazepam, Diazepam, Doxycycline, Imipramine, kanamycin, Lorazepam, Lynestrenol, Meprobamate, methimazole, Minocycline, oxazepam, Oxytetracycline, Tamoxifen, Tetracycline, Uracil, Voriconazole, and many more. DRUG CATEGORY EXAMPLE X (Generic name): Acitretin, Alprotadil * Parenteral *, Atorvastatin, bicalutamide, bosentan, Cerivastatin disodium, Cetrorelix, Chenodeoxycholic acid, Chlorotrianisene, chorionic gonadotrophin, Clomifen, coumarin, Danazol, Desogestrel, Dienestrol, diethylstilbestrol, Dihydro Ergotamine, Dutasteride, Ergometrin, Ergotamine, Estazolam, Etradiol , Estramustine, Estriol succinate, estrone, Estropipate, ethinyl estradiol, Etretinate, Finasteride, Fluorescein * Parenteral *, Flurouracil, Fluoxymesterone, Flurazepam, Fluvastatin, Floritropin, Ganirelix, Gestodene, Goserelin, Human menopausal gonadotrophin, Iodinated glycerol, Isotretinoin, leflunomide, Leuprorelin , Levonorgestrel, Lovastatin, Medrogestrone, medroxyprogesterone, Menotrophin, mestranol, methotrexate, methyl testosterone, Mifeprestone, Miglustat, Misoprostol, Nafarelin, nandrolone, Nicotine * po *, norethisterone, Noretynodrel, norgestrel, Oxandrolone, Oxymetholone, Oxytocin, Pravastatin, quinine, Raloxifene , Ribavirin, rosuvastatin, simvastatin, Stanozolol, tazarotene, temazepam, tetosterone, Thalidomide, triazolam, Triproretin, Urofolitropin, Warfarin.
From the description above, pain relief drugs such as mefenamic acid 500 mg (brand name for example: Ponstan, Ponstelax, Stanza, Opistan, etc) are Category B drug in pregnancy which means SAFE